At 1947 hours, Station 700 was alerted along with Stations 600 (Greensboro), 56 (Marydel), 400 (Ridgely) and 300 (Denton) for an appliance (dryer) fire at 14400 Irwin Chapel Road in the 7-2 Box. Upon responding, the call was upgraded to a working dwelling fire with 3 people reported trapped inside and 1 person who had jumped from a second story window. Engine 703 (717-Wothers) arrived to find a two story wood-framed residence 50% involved and he immediately established “Irwin Chapel Road Command.” Crews quickly put hand lines from Engine 703 and Engine 603 into service. While attempting to enter the house, they encountered heavy fire that had spread rapidly throughout the house and to a detached garage. Additionally, crews found Collyer brothers conditions throughout the structure, making entry and movement extremely difficult. Paramedic 17 (Caroline County EMS - Labrie & Messick) arrived simultaneously and found an unconscious female lying in the driveway suffering from burns and smoke inhalation. Additionally, there were two other residents of the home in need of medical attention due to the fire. All occupants were found to have been evacuated upon the arrival of the first units on the scene. The unconscious female was transported priority 1 to Bayview Burn Center in Baltimore via MSP Trooper 4. The two additional patients (one ALS and one BLS) were transported to Kent General Hospital in Dover, DE by ground units. Based on the difficult circumstances presented, a decision was made to attack the fire defensively. Due to the rural setting, additional tankers were requested from the surrounding area. Although the situation was placed under control at 2139 hours, the last unit cleared the scene at 0117 hours. In addition to the previously mentioned companies, Goldsboro VFC was assisted on the scene by Talbot County Station 80 (Queen-Anne Hillsboro), Kent County, DE Station 48 (Felton) Queen Anne’s County DES, Choptank Electric, the Red Cross and the Caroline County Humane Society. The members of Station 700 thank all of the mutual aid companies for their assistance. A special thank you goes out to the stand-by crew from Queen Anne’s County Station 5 (Church Hill) who provided coverage during our emergency and stayed to help get our engines back in service after returning to quarters.